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Consequently, 4SC-205 gets the potential to generate a therapeutic effect analogous to various other anti-mitotic drugs however avoiding peripheral nerve harm commonly seen after taxane chemotherapy. In preclinical research 4SC-205 displayed encouraging anti-tumour activity in a number of in vitro and in vivo versions. Dr Bernd Hentsch, Chief Development Officer of 4SC commented, ‘With the commencement of this trial, we have now extended our oncology pipeline to add a third compound. This anti-mitotic agent, predicated on earlier preclinical outcomes, could be positioned in a variety of cancer indications. During the last twelve months 4SC has now established a strong, clinical stage oncology investigating multiple, innovative approaches for the treating both haematological and solid cancers.’..