In an article published online June 6.

A significant development in recent years may be the discovery that some people with epilepsy have subtle mind malformations that arose through the early advancement of the brain. Carmant and his group have hypothesized that such abnormalities might remain harmless unless a young child encounters atypical febrile seizures. They have been in a position to try this hypothesis by creating brain malformations just after birth in rat pups. In earlier studies, we showed that that atypical febrile seizures occur only in rat pups with an underlying delicate cortical malformation, stated Carmant.Second Quarter 2010 Highlights Pipeline advancement Perifosine – April 5, 2010: Perifosine receives U.S. Food and Drug Administration Fast Monitor Designation for the Phase 3 X-PECT + Perifosine Evaluation in Colorectal cancer tumor Treatment) registration trial. April 8 -, 2010: Initiation of the registration Phase 3 X-PECT study with perifosine. – April 15, 2010: Positive Scientific Guidance from the European Medicines Agency for the Stage 3 program with perifosine in multiple myeloma.