Seung-Jung Recreation area.
There were no significant between-group differences in the cumulative incidence rates of the individual components of the primary end point at 1 year, including death, myocardial infarction, stroke, ischemia-driven target-vessel revascularization, and the composite of death, myocardial infarction, or stroke . When the follow-up evaluation was extended to 24 months, there were no significant variations in the incidence rates of the primary composite end point or the individual end points of loss of life, myocardial infarction, or stroke . Nevertheless, the 2-year rate of ischemia-driven target-vessel revascularization was low in the CABG group than in the PCI group significantly. The prices of clinically powered target-vessel revascularization didn’t differ significantly between the groups . Based on the Academic Research Consortium classification,22 definite or probable stent thrombosis occurred in two patients in the PCI group over the course of 2 years.Genetic Research SNP array analysis in the index individual revealed 36 homozygous genomic regions larger than 1 Mb, with 7 of the 36 larger than 10 Mb, which verified consanguinity. Targeted exome sequencing of coding elements of these homozygous areas in the five family members yielded nine rare variants. Of these, a single-nucleotide insertion disrupting the reading body of MCT1 at asparagine 15 was the strongest candidate. The right segregation of this mutation in the family members was confirmed by means of Sanger sequencing. This variant was absent from multiple huge variation databases . The insertion of an extra nucleotide early in the gene sequence outcomes in a frameshift and thus in a loss of MCT1 function.