The price of health care pushes some 39 million people back into poverty.
AP/Seattle Times examines health care costs in India The Associated Press/Seattle Occasions examines the challenges associated with extending affordable health care to people in India. Every year, the price of health care pushes some 39 million people back into poverty, according to a report released in the Lancet medical journal. Individuals shoulder up to 80 % of India’s medical costs. While India features an economic growth price near 9 %, the wealth did little to help millions burdened by disease and poverty. The poor, aside from struggling to afford care, also face intense shortages of doctors and medications .The cellular prosurvival proteins Bcl-xL is usually up-regulated in patients with CML and polycythemia vera and can be considered to inhibit apoptosis.4-7 Moreover, BCR-ABL proteins expression is associated with a reduced apoptotic response to genotoxic drugs,8 and quiescent CML stem cells, thought to be responsible for residual disease, are resistant to the apoptosis that tyrosine kinase inhibitors induce.9-11 A pathway regulating the function of Bcl-xL has been described in several studies. In this context, the importance of deamidation is because of its transformation of the amino acid asparagine into isoaspartic acid.13,14 Thymocytes that were transformed by an activated Lck tyrosine kinase were unable to respond to DNA damage by increasing NHE-1 amounts, Bcl-xL deamidation, or apoptosis.14 As the relevance of Bcl-xL deamidation for human being cancers connected with activated tyrosine kinases continues to be unclear, we examined the Bcl-xL deamidation pathway in cells from individuals with CML and polycythemia vera.